KLOW Blend
Batch documentation. Ask what exists for the batch we would ship before you order — email us ›
BPC-157 + GHK-Cu + TB-500 + KPV
A research blend of BPC-157, GHK-Cu, TB-500 and KPV combining components studied in cell-migration, skin-matrix and inflammatory-signalling research.
Mechanism#
Builds on the GLOW combination by adding KPV, a C-terminal tripeptide of α-MSH — studied as a four-peptide blend spanning cell-migration, skin-matrix and inflammatory-signalling research.
Areas of research#
- Combined cell-migration research
- Inflammatory-signalling models
- Collagen and skin-remodeling
- Multi-peptide research
Sizes and pricing#
| Size | Price per vial | Availability |
|---|---|---|
| 80mg | £82 | In stock |
Buying more than one? Mix and match any peptide vials: 3 vials 8%, 5 vials 12%, 10 or more 15% off the peptides in your basket. You get whichever is better, the bulk or the volume discount, never both — applied automatically at checkout. How it works.
Check your certificate#
- BPC-157: 1419.55 (monoisotopic 1418.70), seen as ions near 1419.7 and 710.4.
- GHK-Cu: 401.91 for the copper complex, C14H22CuN6O4. 340.38 is free GHK, the tripeptide without its copper.
- TB-500: 4963.44 for full-length thymosin β4. A mass near 889 is the seven-residue fragment sold under the same name, a different substance.
- KPV: 342.4 as the free acid, 341.5 as the amide, about one apart. The certificate should say which form it describes. 344.4 is Lys-Pro-Thr, a different peptide.
- Each component on its own line. A blend certificate should identify and quantify all four separately, with purity, if reported, given per component and the method named. Our blend certificates report quantity rather than mass, so the TB-500’s identity rests on the manufacturer’s certificate for the source material.
Ask about the documentation for the batch we would ship before you order. How to check a certificate yourself: verifying a COA.
What’s in the vial#
| Fill | 80mg vial |
|---|---|
| Components | BPC-157, GHK-Cu, TB-500 (full-length thymosin β4) and KPV, pre-mixed in one vial |
| Copper | About 15.8% of GHK-Cu’s weight is copper, not peptide. |
| Purity and content | Purity is the share of what was detected that is each named peptide. Net peptide content, how much of the powder’s weight is peptide rather than salt and water, is a separate number. How much is in the vial. |
Handling at a glance#
| Solvent | Bacteriostatic or sterile water |
|---|---|
| Sealed vial | 2–8°C, protected from light and moisture. Let it reach room temperature before opening. |
| Once in solution | 2–8°C and dark. Avoid thawing and refreezing the same volume. |
| Worth knowing | Where a blend contains GHK-Cu, the copper peptide’s handling applies to the whole preparation: light protection, gentle reconstitution, cold storage. Strongly acidic conditions strip the copper and leave free GHK. |
Working out a concentration: the reconstitution calculator. Technique: the reconstitution guide and the storage guide.
What the research covers#
The guide linked here covers how a blend should be checked, not a study of the combination. For the components: published work on BPC-157 is overwhelmingly in rodents, and a 2026 systematic review of the human evidence found three small uncontrolled studies with 30 participants in total. GHK-Cu has several decades of literature, mostly cell and animal studies and cosmetic-ingredient work. The thymosin β4 literature is overwhelmingly preclinical. KPV’s is small and preclinical, cell culture and mostly mouse colitis models, with no published human clinical trial that we have found. None of the four is a licensed medicine in the UK. Read the full guide, with sources: How Peptide Blend Research Kits Should Be Checked.
Published literature#
- Esposito S, Deventer K, Goeman J, et al. (2012). Drug Test Anal 4(9):733–8. An anti-doping laboratory in Ghent identifies the acetylated 17–23 fragment, Ac-LKKTETQ, in a product sold as TB-500, and synthesises it as a reference standard. PubMed 22962027
- Sikirić P, Petek M, Rucman R, et al. (1993). J Physiol Paris 87(5):313–27. The Zagreb group’s early overview, introducing the 15-residue fragment and summarising their animal studies. PubMed 8298609
- Chang CH, Tsai WC, Lin MS, et al. (2011). J Appl Physiol (1985) 110(3):774–80. Independent study from Chang Gung University, Taiwan, of rat tendon fibroblasts with BPC-157: outgrowth from tendon explants, cell survival under oxidative stress, and migration. PubMed 21030672
- Mortazavi SM, Mohammadi Vadoud SA, Moghimi HR (2025). Bioimpacts 15:30071. Independent review of GHK and GHK-Cu as topical cosmetic ingredients, covering cell studies, skin permeability and formulation. Notes that GHK-Cu is widely used in cosmetic products. PubMed 39963574
- Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al. (2008). Gastroenterology 134(1):166–78. Cell and mouse study from Emory University, Atlanta, of KPV uptake through the PepT1 di- and tripeptide transporter in intestinal and immune cells, and of NF-κB and MAP kinase signalling. PubMed 18061177
Listed so the work can be read at source. A paper on this list is evidence of what was studied, not of what any product does.
Questions#
What is in the vial?
Four peptides pre-mixed in one 80mg vial: BPC-157, GHK-Cu (the copper complex of the tripeptide GHK), TB-500 (full-length thymosin β4) and KPV (Lys-Pro-Val, the last three residues of α-MSH).
What molecular weight should the certificate show?
One figure for each component: 1419.55 for BPC-157, 401.91 for the GHK-Cu copper complex, 4963.44 for TB-500 as full-length thymosin β4, and 342.4 for KPV as the free acid or 341.5 as the amide. The certificate should say which KPV form it describes.
How should it be stored?
Sealed vial at 2-8°C, protected from light and moisture. Once reconstituted with bacteriostatic or sterile water, keep it at 2-8°C in the dark, avoid thawing and refreezing the same volume, and avoid strongly acidic conditions, which strip the copper from GHK-Cu.
Is there a batch certificate?
Yes. The certificate for the current batch is available on request: email orders@pioneerpeptides.co.uk with the product and size.
Is it for human use?
No. It is supplied for laboratory research only, and we do not give guidance on human or animal use.
A batch-specific Certificate of Analysis is available on request. New to handling lyophilised material? See our reconstitution guide, storage guide and how to read a COA.